Highly pathogenic avian influenza (HPAI) viruses

Highly pathogenic avian influenza

Context:

  • Most avian flu outbreaks in India reported from post-monsoon to pre-summer season: study.
  • HPAI H5N1 viruses are constantly evolving globally through complex genetic changes, which have infected poultry, wild birds, as well as humans – study

About Influenza:

There are 4 types of influenza viruses: types A, B, C and D:

Influenza AInfluenza BInfluenza CInfluenza D
Infect humans and many different animals.
The emergence of a new and very different influenza A virus with the ability to infect people and have sustained human-to-human transmission, can cause an influenza pandemic.  
Infect humans and many different animals.
The emergence of a new and very different influenza A virus with the ability to infect people and have sustained human-to-human transmission, can cause an influenza pandemic.  
Infect both humans and pigs but infections are generally mild and are rarely reportedPrimarily affect cattle and are not known to infect or cause illness in people.  

Influenza type A viruses:

  • They are of most significance to public health due to their potential to cause an influenza pandemic.
  • Influenza type A viruses are classified into subtypes according to the combinations of different virus surface proteins hemagglutinin (HA) and neuraminidase (NA).
  • So far there are 18 different hemagglutinin subtypes and 11 different neuraminidase subtypes. (need not learn the numbers for exam given here to build a perception)
  • Depending on the origin host, influenza A viruses can be classified as avian influenza, swine influenza, or other types of animal influenza viruses. 
  • Examples include
    • Avian influenza “bird flu” virus subtypes A(H5N1) and A(H9N2)
    • Swine influenza “swine flu” virus subtypes A(H1N1) and A(H3N2)
  • All of these animal influenza type A viruses are distinct from human influenza viruses and do not easily transmit among humans.
  • Avian influenza A viruses rarely infect people. 
  • Aquatic birds are the primary natural reservoir for most subtypes of influenza A viruses.

Avian influenza A viruses are classified into the following two categories: low pathogenicity avian influenza (LPAI) A viruses, and highly pathogenic avian influenza (HPAI) A viruses.

Low pathogenic avian influenza virusesHighly pathogenicavian influenza viruses
Cause either no signs of disease or mild disease in chickens/poultry. In poultry, some low-pathogenic viruses can mutate into highly pathogenic avian influenza viruses. Cause severe disease and high mortality in infected poultry.  Only some avian influenza A(H5) and A(H7) viruses are classified as HPAI A viruses.

Read about the Spanish flu

Source: The Hindu


Previous year question

H1N1 virus is sometimes mentioned in the news with reference to which one of the following diseases?

[UPSC Civil Services Exam – 2015 Prelims]

(a) AIDS
(b) Bird flu
(c) Dengue
(d) Swine flu

Answer: (d) 

Consider the following statements:

1. In tropical regions, Zika virus disease is transmitted by ‘the same mosquito that transmits dengue.
2. Sexual transmission of Zika virus disease is possible

Which of the statements given above is/are correct?

[UPSC Civil Services Exam – 2017 Prelims]

(a) 1 only
(b) 2 only
(c) Both 1 and 2
(d) Neither 1 nor 2

Answer: (c) 

Practice question

Consider the following statements about influenza virus

  1. Influenza type D viruses are of most significance to public health due to their potential to cause an influenza pandemic.
  2. Aquatic birds are the primary natural reservoir for most subtypes of influenza A viruses.

Which of the above statement/s is/are correct?

 
 
 
 

Question 1 of 1

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